Why glycobiology is revolutionary for the treatment of dry and sensitive skin

Glycobiology is one of the latest revolutions in dermatology.

Glycobiology is the science of glycans

Glycans are complex sugars found in skin cells. They help reduce skin sensitivity, improve hydration and slow down cellular aging, by reactivating exchange processes in the epidermis and dermis.

Why do glycans have a fundamental role in cellular communication and cutaneous biological mechanisms (and therefore in the proper functioning of the skin)?

Keratinocytes (cells constituting 90% of the epidermis and skin appendages) have receptors on their surface necessary for cellular communication and the activation of numerous physiological reactions. These receptors, called lectins, have a particular affinity for glycans.

How cellular communication (and glycans) impacts skin quality

As we age, cellular exchanges become more difficult, which causes skin dryness, redness, hyperreactivity, wrinkles, loss of firmness, etc. Introduced in cosmetics, the attachment of glycans to keratinocyte receptors allows the propagation of biological messages and thus regulation. of various processes such as inflammation, dehydration and cell turnover.

In addition to improving skin cellular communication, glycans influence neuronal communication, and thus limit the hyper-reactivity of the skin.

Modulating keratinocyte communication alone cannot achieve skin comfort, particularly with regard to soothing irritation in reactive and sensitive skin. Indeed, in this case neuronal communication plays a fundamental role. Every day, external stimuli such as pollution or chemicals cause neurogenic inflammation reactions through the activation of sensitivity receptors in the skin. Given its ability to positively influence keratinocyte communication, glycans have a strong potential to modulate neuronal communication and thus limit the hyper-reactivity of sensory nerve fibers by inhibiting the activation of these receptors.

Conclusion: glycans derive their biological effectiveness from their ability to modulate both keratinocyte and neuronal communication within the skin, due to their affinity for the fucose lectins of keratinocytes but also their unique ability to reduce neuronal sensitivity via the ASIC receptor pathway.

In which Apicia product can we find glycans?

Find glycans (a polysaccharide rich in fucose) in our ORGANIC DRY AND SENSITIVE SKIN CARE at a record concentration of 10%!

Immediate soothing, reducing skin sensitivity, hydrating, anti-aging and restructuring, our organic dry and sensitive skin treatment is indicated for sensitive, fragile, delipidated or dehydrated skin. It restores the quality of the skin barrier and considerably limits the appearance of feelings of tightness, irritation and discomfort, thanks to this revolutionary new science in dermatology that is glycobiology.